Stable networks of water-mediated interactions are conserved in activation of diverse GPCRs
Stable networks of water-mediated interactions are conserved in activation of diverse GPCRs
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
G protein-coupled receptors (GPCRs) have evolved to recognize incredibly diverse extracellular ligands while sharing a common architecture and structurally conserved intracellular signaling partners. It remains unclear how binding of diverse ligands brings about GPCR activation, the common structural change that enables intracellular signaling. Her...
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Full title
Stable networks of water-mediated interactions are conserved in activation of diverse GPCRs
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TN_cdi_proquest_journals_2068560303
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068560303
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E-ISSN
2692-8205
DOI
10.1101/351502
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https://www.proquest.com/docview/2068560303?pq-origsite=primo&accountid=13902
