The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk
The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk
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Author / Creator
Deming, Yuetiva , Filipello, Fabia , Cignarella, Francesca , Hsu, Simon , Mikesell, Robert , Li, Zeran , Del-Aguila, Jorge L , Dube, Umber , Farias, Fabiana G , Bradley, Joseph , Cantoni, Claudia , Benitez, Bruno , Budde, John , Ibanez, Laura , Fernandez, Maria V , Blennow, Kaj , Nellgard, Bengt , Zetterberg, Henrik , Heslegrave, Amanda , Johansson, Per M , Svensson, Johan , Lleo, Alberto , Alcolea, Daniel , Clarimon, Jordi , Rami, Lorena , Molinuevo, Jose Luis , Suarez-Calvet, Marc , Morenas-Rodriguez, Estrella , Kleinberger, Gernot , Ewers, Michael , Brett, Thomas J , Haass, Christian , Harari, Oscar , Karch, Celeste M , Piccio, Laura and Cruchaga, Carlos
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) levels in the cerebrospinal fluid (CSF) have been associated with Alzheimer disease (AD) status. TREM2 plays a critical role in microglial activation, survival, and phagocytosis; however, the pathophysiological role of sTREM2 in AD is not well understood. Understanding the role of sT...
Alternative Titles
Full title
The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk
Authors, Artists and Contributors
Author / Creator
Filipello, Fabia
Cignarella, Francesca
Hsu, Simon
Mikesell, Robert
Li, Zeran
Del-Aguila, Jorge L
Dube, Umber
Farias, Fabiana G
Bradley, Joseph
Cantoni, Claudia
Benitez, Bruno
Budde, John
Ibanez, Laura
Fernandez, Maria V
Blennow, Kaj
Nellgard, Bengt
Zetterberg, Henrik
Heslegrave, Amanda
Johansson, Per M
Svensson, Johan
Lleo, Alberto
Alcolea, Daniel
Clarimon, Jordi
Rami, Lorena
Molinuevo, Jose Luis
Suarez-Calvet, Marc
Morenas-Rodriguez, Estrella
Kleinberger, Gernot
Ewers, Michael
Brett, Thomas J
Haass, Christian
Harari, Oscar
Karch, Celeste M
Piccio, Laura
Cruchaga, Carlos
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2068570782
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068570782
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/352179
How to access this item
https://www.proquest.com/docview/2068570782?pq-origsite=primo&accountid=13902
