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Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068836146

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Most patients with advanced cancer eventually acquire resistance to targeted therapies, spurring extensive efforts to identify molecular events mediating therapy resistance. Many of these events involve synthetic rescue (SR) interactions, where the reduction in cancer cell viability caused by targeted gene inactivation is rescued by an adaptive alt...

Alternative Titles

Full title

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068836146

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068836146

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/284240