Atomic structure of the mitochondrial inner membrane AAA+ protease YME1 reveals the mechanism of sub...
Atomic structure of the mitochondrial inner membrane AAA+ protease YME1 reveals the mechanism of substrate processing
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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We present the first atomic model of a substrate-bound inner mitochondrial membrane AAA+ quality control protease, YME1. Our ~3.4 cryo-EM structure reveals how the ATPases form a closed spiral staircase encircling an unfolded substrate, directing it toward the flat, symmetric protease ring. Importantly, the structure reveals how three coexisting nu...
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Atomic structure of the mitochondrial inner membrane AAA+ protease YME1 reveals the mechanism of substrate processing
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TN_cdi_proquest_journals_2069685607
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069685607
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E-ISSN
2692-8205
DOI
10.1101/189316
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https://www.proquest.com/docview/2069685607?pq-origsite=primo&accountid=13902
