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Improving on a modal-based estimation method: model averaging for consistent and efficient estimatio...

Improving on a modal-based estimation method: model averaging for consistent and efficient estimatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069727729

Improving on a modal-based estimation method: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

About this item

Full title

Improving on a modal-based estimation method: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Background: A robust method for Mendelian randomization does not require all genetic variants to be valid instruments to give consistent estimates of a causal parameter. Several such methods have been developed, including a mode-based estimation method giving consistent estimates if a plurality of genetic variants are valid instruments; that is, th...

Alternative Titles

Full title

Improving on a modal-based estimation method: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2069727729

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069727729

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/175372