Study design of multi-center, open-label randomized controlled, head-to-head trial comparing minodro...
Study design of multi-center, open-label randomized controlled, head-to-head trial comparing minodronic acid and raloxifene: Japanese Osteoporosis Intervention Trial (JOINT)-04
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Author / Creator
Adequate Treatment of Osteoporosis (A-TOP) research group , Uemura, Yukari , Tanaka, Shiro , Miyazaki, Teruhiko , Tsukiyama, Mayumi , Sone, Teruki , Taguchi, Akira , Soen, Satoshi , Mori, Satoshi , Hagino, Hiroshi , Sugimoto, Toshitsugu , Fukunaga, Masao , Ohta, Hiroaki , Nakamura, Toshitaka , Orimo, Hajime and Shiraki, Masataka
Publisher
Tokyo: Springer Japan
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Language
English
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Publisher
Tokyo: Springer Japan
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Contents
We planned to conduct multi-center, open-labeled, blinded-endpoints, head-to-head randomized trial of minodronate and raloxifene to compare incidences of vertebral and non-vertebral fractures. The study is the Japanese Osteoporosis Intervention Trial protocol number 4 (JOINT-4). Here, we present the pre-fixed study design. The inclusion criteria ar...
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Full title
Study design of multi-center, open-label randomized controlled, head-to-head trial comparing minodronic acid and raloxifene: Japanese Osteoporosis Intervention Trial (JOINT)-04
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Record Identifier
TN_cdi_proquest_journals_2071020318
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071020318
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ISSN
0914-8779
E-ISSN
1435-5604
DOI
10.1007/s00774-018-0942-z