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Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071117583

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

About this item

Full title

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Epigenetic alteration has been implicated in aging. However, the mechanism by which epigenetic change impacts aging is unclear. H3K27me3, a highly conserved histone modification signifying transcriptional repression, is marked and maintained by Polycomb Repressive Complexes (PRCs). Here, we explore the mechanism by which age-modulated increase of H...

Alternative Titles

Full title

Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071117583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071117583

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/247726