Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity
Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity
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Ma, Zaijun , Wang, Hui , Cai, Yuping , Wang, Han , Niu, Kongyan , Wu, Xiaofen , Ma, Huanhuan , Yang, Yun , Tong, Wenhua , Liu, Feng , Liu, Zhandong , Zhang, Yaoyang , Liu, Rui , Zheng-Jiang, Zhu and Liu, Nan
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Epigenetic alteration has been implicated in aging. However, the mechanism by which epigenetic change impacts aging is unclear. H3K27me3, a highly conserved histone modification signifying transcriptional repression, is marked and maintained by Polycomb Repressive Complexes (PRCs). Here, we explore the mechanism by which age-modulated increase of H...
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Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity
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TN_cdi_proquest_journals_2071117583
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071117583
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E-ISSN
2692-8205
DOI
10.1101/247726
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https://www.proquest.com/docview/2071117583?pq-origsite=primo&accountid=13902