A single-cell catalogue of regulatory states in the ageing Drosophila brain
A single-cell catalogue of regulatory states in the ageing Drosophila brain
About this item
Full title
Author / Creator
Davie, Kristofer , Janssens, Jasper , Koldere, Duygu , Pech, Uli , Aibar, Sara , De Waegeneer, Maxime , Makhzami, Samira , Christiaens, Valerie , Carmen Bravo Gonzalez-Blas , Hulselmans, Gert , Spanier, Katina , Moerman, Thomas , Vanspauwen, Bram , Lammertyn, Jeroen , Thienpont, Bernard , Liu, Sha , Verstreken, Patrik and Aerts, Stein
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
The diversity of cell types and regulatory states in the brain, and how these change during ageing, remains largely unknown. Here, we present a single-cell transcriptome catalogue of the entire adult Drosophila melanogaster brain sampled across its lifespan. Both neurons and glia age through a process of "regulatory erosion", characterized by a str...
Alternative Titles
Full title
A single-cell catalogue of regulatory states in the ageing Drosophila brain
Authors, Artists and Contributors
Author / Creator
Janssens, Jasper
Koldere, Duygu
Pech, Uli
Aibar, Sara
De Waegeneer, Maxime
Makhzami, Samira
Christiaens, Valerie
Carmen Bravo Gonzalez-Blas
Hulselmans, Gert
Spanier, Katina
Moerman, Thomas
Vanspauwen, Bram
Lammertyn, Jeroen
Thienpont, Bernard
Liu, Sha
Verstreken, Patrik
Aerts, Stein
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2071126860
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071126860
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/237420
How to access this item
https://www.proquest.com/docview/2071126860?pq-origsite=primo&accountid=13902
