Development of photoactivatable drugs enables nicotinic optopharmacology
Development of photoactivatable drugs enables nicotinic optopharmacology
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Photoactivatable ('caged') pharmacological agents have revolutionized neuroscience but the palette of available ligands is limited. We describe a general method for caging tertiary amines using an unconventional quaternary ammonium linkage that is chemically stable and elicits a desirable red-shift in activation wavelength. A photoactivatable nicot...
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Full title
Development of photoactivatable drugs enables nicotinic optopharmacology
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TN_cdi_proquest_journals_2071179305
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071179305
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E-ISSN
2692-8205
DOI
10.1101/260232
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https://www.proquest.com/docview/2071179305?pq-origsite=primo&accountid=13902
