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PLK1 plays dual roles in centralspindlin regulation during cytokinesis

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071229293

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

About this item

Full title

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Cytokinesis starts in anaphase with the formation of an actomyosin-based contractile ring at the equatorial cortex, which is governed by the local activation of the small GTPase RhoA. Here we delineated the contributions of PLK1 and Aurora B to RhoA activation and cytokinesis initiation in human cells. Knock-down of PRC1, which disrupts the spindle...

Alternative Titles

Full title

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071229293

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071229293

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/317388