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COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus

COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071247976

COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus

About this item

Full title

COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The respiratory tract is normally kept essentially free of bacteria by cilia-mediated mucus transport, but in chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) mucus accumulates due to goblet cell hyperplasia and mucin overexpression. To address mechanisms behind the mucus accumulation, the elastase-induced mouse model was utili...

Alternative Titles

Full title

COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071247976

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071247976

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/205948