Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in ca...
Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The Maternal Embryonic Leucine Zipper Kinase (MELK) has been identified as a promising therapeutic target in multiple cancer types. MELK over-expression is associated with aggressive disease, and MELK has been implicated in numerous cancer-related processes, including chemotherapy resistance, stem cell renewal, and tumor growth. Here, we report tha...
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Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer
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TN_cdi_proquest_journals_2071252234
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071252234
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E-ISSN
2692-8205
DOI
10.1101/203984
How to access this item
https://www.proquest.com/docview/2071252234?pq-origsite=primo&accountid=13902
