Therapeutic target discovery using Boolean network attractors: avoiding pathological phenotypes
Therapeutic target discovery using Boolean network attractors: avoiding pathological phenotypes
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Ithaca: Cornell University Library, arXiv.org
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English
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Publisher
Ithaca: Cornell University Library, arXiv.org
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Contents
Target identification, one of the steps of drug discovery, aims at identifying biomolecules whose function should be therapeutically altered in order to cure the considered pathology. This work proposes an algorithm for in silico target identification using Boolean network attractors. It assumes that attractors of dynamical systems, such as Boolean...
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Full title
Therapeutic target discovery using Boolean network attractors: avoiding pathological phenotypes
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TN_cdi_proquest_journals_2082328792
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2082328792
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E-ISSN
2331-8422
DOI
10.48550/arxiv.1407.4374
