Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer's di...
Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer's disease
About this item
Full title
Author / Creator
Pickett, Eleanor K , Herrmann, Abigail G , Mcqueen, Jamie , Abt, Kimberly , Dando, Owen , Tulloch, Jane , Jain, Pooja , Dunnett, Sophie , Sohrabi, Sadaf , Fjeldstad, Maria , Calkin, Will , Murison, Leo , Jackson, Rosemary J , Makis Tzioras , Stevenson, Anna , D'orange, Marie , Hooley, Monique , Davies, Caitlin , Oren, Iris , Rose, Jamie , Mckenzie, Chris-Anne , Allison, Elizabeth , Smith, Colin , Hardt, Oliver , Henstridge, Christopher M , Hardingham, Giles and Spires-Jones, Tara
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
One of the key knowledge gaps blocking development of effective therapeutics for Alzheimer's disease (AD) is the lack of understanding of how amyloid beta (A ) and tau cooperate in causing disease phenotypes. Within a mouse tau deficient background, we probed the molecular, cellular and behavioural disruption triggered by wild-type human tau's infl...
Alternative Titles
Full title
Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Herrmann, Abigail G
Mcqueen, Jamie
Abt, Kimberly
Dando, Owen
Tulloch, Jane
Jain, Pooja
Dunnett, Sophie
Sohrabi, Sadaf
Fjeldstad, Maria
Calkin, Will
Murison, Leo
Jackson, Rosemary J
Makis Tzioras
Stevenson, Anna
D'orange, Marie
Hooley, Monique
Davies, Caitlin
Oren, Iris
Rose, Jamie
Mckenzie, Chris-Anne
Allison, Elizabeth
Smith, Colin
Hardt, Oliver
Henstridge, Christopher M
Hardingham, Giles
Spires-Jones, Tara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2089005086
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2089005086
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/393405
How to access this item
https://www.proquest.com/docview/2089005086?pq-origsite=primo&accountid=13902