Intrinsic Mechanisms Regulating T Cell Tolerance in Autoimmune Diabetes
Intrinsic Mechanisms Regulating T Cell Tolerance in Autoimmune Diabetes
Intrinsic Mechanisms Regulating T Cell Tolerance in Autoimmune Diabetes
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Author / Creator
Publisher
ProQuest Dissertations & Theses
Date
2018
Language
English
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Publisher
ProQuest Dissertations & Theses
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Scope and Contents
Contents
Type 1 Diabetes (T1D) is a polygenic autoimmune disease characterized by immune cell infiltration into the islets of Langerhans, destruction of insulin-producing β cells, and uncontrolled hyperglycemia. Islet-antigen reactive CD4+ and CD8+ T cells, and regulatory T cells (Tregs) are the major players in T1D pathogenesis. Both cell-intrinsic and cel...
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Full title
Intrinsic Mechanisms Regulating T Cell Tolerance in Autoimmune Diabetes
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TN_cdi_proquest_journals_2099251521
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2099251521
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ISBN
9780438364943,0438364945
