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A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2115640642

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

About this item

Full title

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2018-11, Vol.35 (11), p.223-10, Article 223

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
Immunogenicity of PEGylated proteins and nanomedicines represents a potential impediment against their development and use in clinical settings. The purpose of this study is to develop a method for detecting anti-PEG immunity of PEGylated proteins and/or nanomedicines using flow cytometry.
Methods
The binding of fluorescence-labele...

Alternative Titles

Full title

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2115640642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2115640642

Other Identifiers

ISSN

0724-8741

E-ISSN

1573-904X

DOI

10.1007/s11095-018-2505-3

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