A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics
A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Purpose
Immunogenicity of PEGylated proteins and nanomedicines represents a potential impediment against their development and use in clinical settings. The purpose of this study is to develop a method for detecting anti-PEG immunity of PEGylated proteins and/or nanomedicines using flow cytometry.
Methods
The binding of fluorescence-labele...
Alternative Titles
Full title
A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics
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Record Identifier
TN_cdi_proquest_journals_2115640642
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2115640642
Other Identifiers
ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-018-2505-3