RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an e...
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression
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Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
Background
We had previously established that inactivation of RUNX3 occurs by frequent promoter hypermethylation and protein mislocalization in invasive ductal carcinomas (IDC) of breast. Here, we hypothesize that inactivation of RUNX3 occurring in ductal carcinoma in situ (DCIS) represent early event in breast carcinogenesis.
Methods
The...
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Full title
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression
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TN_cdi_proquest_journals_212449758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_212449758
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ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-008-9917-4
