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Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Path...

Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Path...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_212454626

Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1

About this item

Full title

Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1

Publisher

Dordrecht: Springer

Journal title

Breast cancer research and treatment, 2001-05, Vol.67 (1), p.23-33

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer

More information

Scope and Contents

Contents

Overexpression of the cyclin D1 (CCND1) gene, encoding a downstream effector of mitogenic signals that plays a central role in G1 phase progression, is often found in cancerous cells. In sporadic breast cancer (BC), this is one of the most frequent and early genetic lesions identified so far, found in more than 50% of the tumors. Inhibitors of the...

Alternative Titles

Full title

Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_212454626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_212454626

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1023/A:1010675310188

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