BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr...
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
About this item
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Author / Creator
Sartori, Maxime , Mendes, Tiago , Desai, Shruti , Lasorsa, Alessia , Herldean, Adrien , Malmanche, Nicolas , Makinen, Petra , Marttinen, Mikael , Malki, Idir , Chapuis, Julien , Flaig, Amandine , Anais-Camille Vreulx , Amouyel, Philippe , Leroux, Florence , Deprez, Benoit , Francois-Xavier Cantrelle , Marechal, Damien , Pradier, Laurent , Hiltunen, Mikko , Landrieu, Isabelle , Kilinc, Devrim , Herault, Yann , Laporte, Jocelyn and Lambert, Jean-Charles
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice either overexpressing human MAPT (TgMAPT) or both human MAPT and BIN1 (TgMAPT;TgBIN1...
Alternative Titles
Full title
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
Authors, Artists and Contributors
Author / Creator
Mendes, Tiago
Desai, Shruti
Lasorsa, Alessia
Herldean, Adrien
Malmanche, Nicolas
Makinen, Petra
Marttinen, Mikael
Malki, Idir
Chapuis, Julien
Flaig, Amandine
Anais-Camille Vreulx
Amouyel, Philippe
Leroux, Florence
Deprez, Benoit
Francois-Xavier Cantrelle
Marechal, Damien
Pradier, Laurent
Hiltunen, Mikko
Landrieu, Isabelle
Kilinc, Devrim
Herault, Yann
Laporte, Jocelyn
Lambert, Jean-Charles
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2130626897
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2130626897
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/462317
How to access this item
https://www.proquest.com/docview/2130626897?pq-origsite=primo&accountid=13902
