Pharmacogenomics of Tamoxifen Therapy
Pharmacogenomics of Tamoxifen Therapy
About this item
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Author / Creator
Publisher
Washington, DC: Am Assoc Clin Chem
Journal title
Language
English
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Publication information
Publisher
Washington, DC: Am Assoc Clin Chem
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Scope and Contents
Contents
Tamoxifen is a standard endocrine therapy for the prevention and treatment of steroid hormone receptor-positive breast cancer.
Tamoxifen requires enzymatic activation by cytochrome P450 (CYP) enzymes for the formation of active metabolites 4-hydroxytamoxifen and endoxifen. As compared with the parent drug, both metabolites have an approximately...
Alternative Titles
Full title
Pharmacogenomics of Tamoxifen Therapy
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_213991338
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213991338
Other Identifiers
ISSN
0009-9147
E-ISSN
1530-8561
DOI
10.1373/clinchem.2008.121756
