CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM 2, neuro...
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM 2, neurodegeneration and cognitive decline
About this item
Full title
Author / Creator
the Alzheimer's Disease Neuroimaging Initiative , the Dominantly Inherited Alzheimer Network , Suárez‐Calvet, Marc , Capell, Anja , Araque Caballero, Miguel Ángel , Morenas‐Rodríguez, Estrella , Fellerer, Katrin , Franzmeier, Nicolai , Kleinberger, Gernot , Eren, Erden , Deming, Yuetiva , Piccio, Laura , Karch, Celeste M , Cruchaga, Carlos , Paumier, Katrina , Bateman, Randall J , Fagan, Anne M , Morris, John C , Levin, Johannes , Danek, Adrian , Jucker, Mathias , Masters, Colin L , Rossor, Martin N , Ringman, John M , Shaw, Leslie M , Trojanowski, John Q , Weiner, Michael , Ewers, Michael and Haass, Christian
Publisher
Frankfurt: EMBO Press
Journal title
Language
English
Formats
Publication information
Publisher
Frankfurt: EMBO Press
Subjects
More information
Scope and Contents
Contents
Progranulin (PGRN) is predominantly expressed by microglia in the brain, and genetic and experimental evidence suggests a critical role in Alzheimer's disease (AD). We asked whether PGRN expression is changed in a disease severity‐specific manner in AD. We measured PGRN in cerebrospinal fluid (CSF) in two of the best‐characterized AD patient cohort...
Alternative Titles
Full title
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM 2, neurodegeneration and cognitive decline
Authors, Artists and Contributors
Author / Creator
the Dominantly Inherited Alzheimer Network
Suárez‐Calvet, Marc
Capell, Anja
Araque Caballero, Miguel Ángel
Morenas‐Rodríguez, Estrella
Fellerer, Katrin
Franzmeier, Nicolai
Kleinberger, Gernot
Eren, Erden
Deming, Yuetiva
Piccio, Laura
Karch, Celeste M
Cruchaga, Carlos
Paumier, Katrina
Bateman, Randall J
Fagan, Anne M
Morris, John C
Levin, Johannes
Danek, Adrian
Jucker, Mathias
Masters, Colin L
Rossor, Martin N
Ringman, John M
Shaw, Leslie M
Trojanowski, John Q
Weiner, Michael
Ewers, Michael
Haass, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2151164520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2151164520
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201809712
