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Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2154259589

Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

About this item

Full title

Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

High levels of the amyloid-beta (Aβ) peptide have been shown to disrupt neuronal function and induce hyperexcitability, but it is unclear what effects Aβ-associated hyperexcitability may have on tauopathy pathogenesis or propagation in vivo. Using a novel transgenic mouse line to model the impact of hAPP/Aβ accumulation on tauopathy in the entorhin...

Alternative Titles

Full title

Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2154259589

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2154259589

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/487405