Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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Author / Creator
Andrew Lee Hong , Yuen-Yi Tseng , Wala, Jeremiah Anthony , Kim, Won Jun , Kynnap, Bryan D , Doshi, Mihir B , Kugener, Guillaume , Sandoval, Gabriel J , Howard, Thomas P , Li, Ji , Yang, Xiaoping , Tillgren, Michelle , Ghandi, Mahmoud , Sayeed, Abeer , Deasy, Rebecca , Ward, Abigail , Mcsteen, Brian , Labella, Katherine M , Keskula, Paula , Adam, Tracy , Connor, Cora , Clinton, Catherine M , Church, Alanna J , Crompton, Brian D , Janeway, Katherine A , Barbara Van Hare , Sandak, David , Gjoerup, Ole , Bandopadhayay, Pratiti , Clemons, Paul A , Schreiber, Stuart L , Root, David E , Gokhale, Prafulla C , Chi, Susan N , Mullen, Elizabeth A , Roberts, Charles Wm , Kadoch, Cigall , Beroukhim, Rameen , Ligon, Keith L , Boehm, Jesse S and Hahn, William
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. Through direct-to-patient outreach, we developed genomically faithful patient-derived models of RMC. Using whole genome sequencing, we identified intronic fusion events in one SMARCB1 allele with concurrent loss of the other all...
Alternative Titles
Full title
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
Authors, Artists and Contributors
Author / Creator
Yuen-Yi Tseng
Wala, Jeremiah Anthony
Kim, Won Jun
Kynnap, Bryan D
Doshi, Mihir B
Kugener, Guillaume
Sandoval, Gabriel J
Howard, Thomas P
Li, Ji
Yang, Xiaoping
Tillgren, Michelle
Ghandi, Mahmoud
Sayeed, Abeer
Deasy, Rebecca
Ward, Abigail
Mcsteen, Brian
Labella, Katherine M
Keskula, Paula
Adam, Tracy
Connor, Cora
Clinton, Catherine M
Church, Alanna J
Crompton, Brian D
Janeway, Katherine A
Barbara Van Hare
Sandak, David
Gjoerup, Ole
Bandopadhayay, Pratiti
Clemons, Paul A
Schreiber, Stuart L
Root, David E
Gokhale, Prafulla C
Chi, Susan N
Mullen, Elizabeth A
Roberts, Charles Wm
Kadoch, Cigall
Beroukhim, Rameen
Ligon, Keith L
Boehm, Jesse S
Hahn, William
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2154274937
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2154274937
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/487579
How to access this item
https://www.proquest.com/docview/2154274937?pq-origsite=primo&accountid=13902
