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Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors
Author / Creator:Milbury, Coren A. ; Creeden, James ; Yip, Wai-Ki ; Smith, David L. ; Pattani, Varun ; Maxwell, Kristi ; Sawchyn, Bethany ; Gjoerup, Ole ; Meng, Wei ; Skoletsky, Joel ; Concepcion, Alvin D. ; Tang, Yanhua ; Bai, Xiaobo ; Dewal, Ninad ; Ma, Pei ; Bailey, Shannon T. ; Thornton, James ; Pavlick, Dean C. ; Frampton, Garrett M. ; Lieber, Daniel ; White, Jared ; Burns, Christine ; Vietz, Christine
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-01, Vol.17 (3), p.e0264138
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STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells
Author / Creator:Kim, Jong Wook ; Berrios, Christian ; Kim, Miju ; Schade, Amy E ; Adelmant, Guillaume ; Yeerna, Huwate ; Damato, Emily ; Iniguez, Amanda Balboni ; Florens, Laurence ; Washburn, Michael P ; Stegmaier, Kim ; Gray, Nathanael S ; Tamayo, Pablo ; Gjoerup, Ole ; Marto, Jarrod A ; DeCaprio, James ; Hahn, William C
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-01, Vol.9
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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus
Author / Creator:Shuda, Masahiro ; Feng, Huichen ; Kwun, Hyun Jin ; Rosen, Steven T ; Gjoerup, Ole ; Moore, Patrick S ; Chang, Yuan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16272-16277
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Functional Connection between Rad51 and PML in Homology-Directed Repair
Author / Creator:Boichuk, Sergei ; Hu, Liang ; Makielski, Kathleen ; Pandolfi, Pier Paolo ; Gjoerup, Ole V.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-10, Vol.6 (10), p.e25814
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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer
Author / Creator:Sivakumar, Smruthy ; Jin, Dexter X. ; Tukachinsky, Hanna ; Murugesan, Karthikeyan ; McGregor, Kimberly ; Danziger, Natalie ; Pavlick, Dean ; Gjoerup, Ole ; Ross, Jeffrey S. ; Harmon, Robert ; Chung, Jon ; Decker, Brennan ; Dennis, Lucas ; Frampton, Garrett M. ; Molinero, Luciana ; Oesterreich, Steffi ; Venstrom, Jeffrey M. ; Oxnard, Geoffrey R. ; Hegde, Priti S. ; Sokol, Ethan S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7495-13, Article 7495
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Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns
Author / Creator:Israel, Mason A. ; Danziger, Natalie ; McGregor, Kimberly A. ; Murugesan, Karthikeyan ; Gjoerup, Ole ; Sokol, Ethan S. ; Tukachinsky, Hanna ; Kurzrock, Razelle ; Kato, Shumei ; Sicklick, Jason K. ; Nimeiri, Halla S. ; Oxnard, Geoffrey R. ; Ross, Jeffrey S.
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The oncologist (Dayton, Ohio), 2021-09, Vol.26 (9), p.787-796
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Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
Author / Creator:Lee, Jessica K. ; Sivakumar, Smruthy ; Schrock, Alexa B. ; Madison, Russell ; Fabrizio, David ; Gjoerup, Ole ; Ross, Jeffrey S. ; Frampton, Garrett M. ; Napalkov, Pavel ; Montesion, Meagan ; Schutzman, Jennifer L. ; Ye, Xin ; Hegde, Priti S. ; Nagasaka, Misako ; Oxnard, Geoffrey R. ; Sokol, Ethan S. ; Ou, Sai-Hong Ignatius ; Shi, Zhen
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2022-12, Vol.6 (1), p.91-14, Article 91
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Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
Author / Creator:Hong, Andrew L ; Tseng, Yuen-Yi ; Wala, Jeremiah A ; Kim, Won-Jun ; Kynnap, Bryan D ; Doshi, Mihir B ; Kugener, Guillaume ; Sandoval, Gabriel J ; Howard, Thomas P ; Li, Ji ; Yang, Xiaoping ; Tillgren, Michelle ; Ghandi, Mahmhoud ; Sayeed, Abeer ; Deasy, Rebecca ; Ward, Abigail ; McSteen, Brian ; Labella, Katherine M ; Keskula, Paula ; Tracy, Adam ; Connor, Cora ; Clinton, Catherine M ; Church, Alanna J ; Crompton, Brian D ; Janeway, Katherine A ; Van Hare, Barbara ; Sandak, David ; Gjoerup, Ole ; Bandopadhayay, Pratiti ; Clemons, Paul A ; Schreiber, Stuart L ; Root, David E ; Gokhale, Prafulla C ; Chi, Susan N ; Mullen, Elizabeth A ; Roberts, Charles WM ; Kadoch, Cigall ; Beroukhim, Rameen ; Ligon, Keith L ; Boehm, Jesse S ; Hahn, William C
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2019-03, Vol.8
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An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
Author / Creator:Li, Ji ; Choi, Peter S ; Chaffer, Christine L ; Labella, Katherine ; Hwang, Justin H ; Giacomelli, Andrew O ; Kim, Jong Wook ; Ilic, Nina ; Doench, John G ; Ly, Seav Huong ; Dai, Chao ; Hagel, Kimberly ; Hong, Andrew L ; Gjoerup, Ole ; Goel, Shom ; Ge, Jennifer Y ; Root, David E ; Zhao, Jean J ; Brooks, Angela N ; Weinberg, Robert A ; Hahn, William C
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2018-07, Vol.7
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Cellular and Viral Factors Regulating Merkel Cell Polyomavirus Replication
Author / Creator:Feng, Huichen ; Kwun, Hyun Jin ; Liu, Xi ; Gjoerup, Ole ; Stolz, Donna B. ; Chang, Yuan ; Moore, Patrick S.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-07, Vol.6 (7), p.e22468
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Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy by Tumor Mutational Burden in Metastatic Castration-Resistant Prostate Cancer
Author / Creator:Graf, Ryon P. ; Fisher, Virginia ; Weberpals, Janick ; Gjoerup, Ole ; Tierno, Marni B. ; Huang, Richard S. P. ; Sayegh, Nicolas ; Lin, Douglas I. ; Raskina, Kira ; Schrock, Alexa B. ; Severson, Eric ; Haberberger, James F. ; Ross, Jeffrey S. ; Creeden, James ; Levy, Mia A. ; Alexander, Brian M. ; Oxnard, Geoffrey R. ; Agarwal, Neeraj
Publisher:United States: American Medical Association
Journal title:JAMA network open, 2022-03, Vol.5 (3), p.e225394
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Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
Author / Creator:Andrabi, Shaida ; Gjoerup, Ole V ; Kean, Jennifer A ; Roberts, Thomas M ; Schaffhausen, Brian
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (48), p.19011-19016
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Liquid Biopsy Profiling with Multiple Tests in Patients with Metastatic Breast Cancer
Author / Creator:Higa, Nikki ; Welter, Lisa ; Xu, Liya ; Kolatkar, Anand ; Bramlett, Kelli S. ; Gjoerup, Ole V. ; Graf, Ryon ; Huang, Richard S.P. ; Leary, Rebecca J. ; Lee, Young ; Perkins, Jeremy G. ; Riker, Adam I. ; Singh, Angad P. ; Tafra, Lorraine ; Tweed, Carol K. ; Shriver, Craig D. ; Hicks, James ; Kuhn, Peter
Publisher:Basel: MDPI AG
Journal title:Journal of Molecular Pathology, 2024-06, Vol.5 (2), p.199-214
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Tissue-based genomic profiling of 300,000 tumors highlights the detection of variants with low allele fraction
Author / Creator:Sisoudiya, Saumya D. ; Tukachinsky, Hanna ; Keller-Evans, Rachel B. ; Schrock, Alexa B. ; Huang, Richard S. P. ; Gjoerup, Ole ; Pishvaian, Michael J. ; Shroff, Rachna ; Sokol, Ethan S. ; Dennis, Lucas ; Frampton, Garrett M. ; Sivakumar, Smruthy
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2025-06, Vol.9 (1), p.190-9, Article 190
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Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA
Author / Creator:Banerjee, Pubali ; deJesus, Rowena ; Gjoerup, Ole ; Schaffhausen, Brian S.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-10, Vol.9 (10), p.e1003725
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Surveillance mechanism linking Bub1 loss to the p53 pathway
Author / Creator:Gjoerup, Ole V ; Wu, Jiaping ; Chandler-Militello, Devin ; Williams, Grace L ; Zhao, Jean ; Schaffhausen, Brian ; Jat, Parmjit S ; Roberts, Thomas M
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (20), p.8334-8339
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The p110α Isoform of PI3K Is Essential for Proper Growth Factor Signaling and Oncogenic Transformation
Author / Creator:Zhao, Jean J. ; Cheng, Hailing ; Jia, Shidong ; Wang, Li ; Gjoerup, Ole V. ; Mikami, Aki ; Roberts, Thomas M.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (44), p.16296-16300
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Simian Virus 40 Large T Antigen Targets the Spindle Assembly Checkpoint Protein Bub1
Author / Creator:Cotsiki, Marina ; Lock, Rowena L. ; Cheng, Yuan ; Williams, Grace L. ; Zhao, Jean ; Perera, David ; Freire, Raimundo ; Entwistle, Alan ; Golemis, Erica A. ; Roberts, Thomas M. ; Jat, Parmjit S. ; Gjoerup, Ole V.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-01, Vol.101 (4), p.947-952
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The Serine/Threonine Kinase Cyclin G-Associated Kinase Regulates Epidermal Growth Factor Receptor Signaling
Author / Creator:Zhang, Lei ; Gjoerup, Ole ; Roberts, Thomas M. ; Collier, R. John
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (28), p.10296-10301
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Identification and Utilization of Biomarkers to Predict Response to Immune Checkpoint Inhibitors
Author / Creator:Gjoerup, Ole ; Brown, Charlotte A. ; Ross, Jeffrey S. ; Huang, Richard S. P. ; Schrock, Alexa ; Creeden, James ; Fabrizio, David ; Tolba, Khaled
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2020-10, Vol.22 (6), p.132, Article 132
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Showing 1 to 20 of 28 results

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Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors

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STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells

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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

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Functional Connection between Rad51 and PML in Homology-Directed Repair

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

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Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns

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Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors

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Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

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An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

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Cellular and Viral Factors Regulating Merkel Cell Polyomavirus Replication

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Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy by Tumor Mutational Burden in Metastatic Castration-Resistant Prostate Cancer

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Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner

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Liquid Biopsy Profiling with Multiple Tests in Patients with Metastatic Breast Cancer

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Tissue-based genomic profiling of 300,000 tumors highlights the detection of variants with low allele fraction

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Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA

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Surveillance mechanism linking Bub1 loss to the p53 pathway

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The p110α Isoform of PI3K Is Essential for Proper Growth Factor Signaling and Oncogenic Transformation

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Simian Virus 40 Large T Antigen Targets the Spindle Assembly Checkpoint Protein Bub1

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The Serine/Threonine Kinase Cyclin G-Associated Kinase Regulates Epidermal Growth Factor Receptor Signaling

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Identification and Utilization of Biomarkers to Predict Response to Immune Checkpoint Inhibitors

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