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Coexpression of (alpha) and (beta) subunits of the rod cyclic GMP-gated channel restores native sens...

Coexpression of (alpha) and (beta) subunits of the rod cyclic GMP-gated channel restores native sens...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_215726443

Coexpression of (alpha) and (beta) subunits of the rod cyclic GMP-gated channel restores native sensitivity to cyclic AMP: Role of D604/N1202

About this item

Full title

Coexpression of (alpha) and (beta) subunits of the rod cyclic GMP-gated channel restores native sensitivity to cyclic AMP: Role of D604/N1202

Publisher

New York: Biophysical Society

Journal title

Biophysical journal, 2000-03, Vol.78 (3), p.1227

Language

English

Formats

Publication information

Publisher

New York: Biophysical Society

More information

Scope and Contents

Contents

To test whether the increased sensitivity to cAMP is due to the uncharged nature of the asparagine residue (N1201) situated in place of aspartate D604 in the beta subunit as previously suggested (Varnum et al., 1995, Neuron. 15:619-625), we compared currents from wild-type (alphawt and alphawt/betawt) and from mutated channels (alphaD604N, alphaD60...

Alternative Titles

Full title

Coexpression of (alpha) and (beta) subunits of the rod cyclic GMP-gated channel restores native sensitivity to cyclic AMP: Role of D604/N1202

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_215726443

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_215726443

Other Identifiers

ISSN

0006-3495

E-ISSN

1542-0086

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