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Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2164393838

Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

About this item

Full title

Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Parkinson's disease (PD) is a progressive neurodegenerative disorder with unknown cause, but it has been postulated that chronic neuroinflammation may play a role in its pathogenesis. Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators. Here, we analyzed the regional distribution and cellular...

Alternative Titles

Full title

Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2164393838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2164393838

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/513671