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ArticlesPeer ReviewedFull Text
Rational design of balanced dual-targeting antibiotics with limited resistance
Author / Creator:Nyerges, Akos ; Tomašič, Tihomir ; Durcik, Martina ; Revesz, Tamas ; Szili, Petra ; Draskovits, Gabor ; Bogar, Ferenc ; Skok, Žiga ; Zidar, Nace ; Ilaš, Janez ; Zega, Anamarija ; Kikelj, Danijel ; Daruka, Lejla ; Kintses, Balint ; Vasarhelyi, Balint ; Foldesi, Imre ; Kata, Diána ; Welin, Martin ; Kimbung, Raymond ; Focht, Dorota ; Mašič, Lucija Peterlin ; Pal, Csaba
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2020-10, Vol.18 (10), p.e3000819
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ArticlesPeer ReviewedFull Text
Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation
Author / Creator:Pišlar, Anja ; Nedeljković, Biljana Božić ; Perić, Mina ; Jakoš, Tanja ; Zidar, Nace ; Kos, Janko
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2022-04, Vol.59 (4), p.2258-2276
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ArticlesPeer ReviewedFull Text
Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors
Author / Creator:Majc, Bernarda ; Habič, Anamarija ; Novak, Metka ; Rotter, Ana ; Porčnik, Andrej ; Mlakar, Jernej ; Župunski, Vera ; Pečar Fonović, Urša ; Knez, Damijan ; Zidar, Nace ; Gobec, Stanislav ; Kos, Janko ; Lah Turnšek, Tamara ; Pišlar, Anja ; Breznik, Barbara
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-02, Vol.23 (3), p.1784
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ArticlesPeer ReviewedFull Text
Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo
Author / Creator:Pišlar, Anja ; Tratnjek, Larisa ; Glavan, Gordana ; Zidar, Nace ; Živin, Marko ; Kos, Janko
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in molecular neuroscience, 2020-11, Vol.13, p.575453-575453
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ArticlesPeer ReviewedFull Text
Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
Author / Creator:Dernovšek, Jaka ; Zajec, Živa ; Durcik, Martina ; Mašič, Lucija Peterlin ; Gobec, Martina ; Zidar, Nace ; Tomašič, Tihomir
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2021-08, Vol.13 (8), p.1283
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ArticlesPeer ReviewedFull Text
Enhancing Antibacterial Efficacy: Combining Novel Bacterial Topoisomerase Inhibitors with Efflux Pump Inhibitors and Other Agents Against Gram-Negative Bacteria
Author / Creator:Zorman, Maša ; Kokot, Maja ; Zdovc, Irena ; Senerovic, Lidija ; Mandic, Mina ; Zidar, Nace ; Cotman, Andrej Emanuel ; Durcik, Martina ; Peterlin Mašič, Lucija ; Minovski, Nikola ; Anderluh, Marko ; Hrast Rambaher, Martina
Publisher:Switzerland: MDPI AG
Journal title:Antibiotics (Basel), 2024-11, Vol.13 (11), p.1081
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ArticlesPeer ReviewedFull Text
Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation
Author / Creator:Durcik, Martina ; Skok, Žiga ; Ilaš, Janez ; Zidar, Nace ; Zega, Anamarija ; Szili, Petra Éva ; Draskovits, Gábor ; Révész, Tamás ; Kikelj, Danijel ; Nyerges, Akos ; Pál, Csaba ; Mašič, Lucija Peterlin ; Tomašič, Tihomir
Publisher:Switzerland: MDPI
Journal title:Pharmaceutics, 2020-12, Vol.13 (1), p.6
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ArticlesPeer ReviewedFull Text
Action of clathrodin and analogues on voltage-gated sodium channels
Author / Creator:Peigneur, Steve ; Zula, Aleš ; Zidar, Nace ; Chan-Porter, Fiona ; Kirby, Robert ; Madge, David ; Ilaš, Janez ; Kikelj, Danijel ; Tytgat, Jan
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2014-04, Vol.12 (4), p.2132-2143
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ArticlesPeer ReviewedFull Text
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action
Author / Creator:Lecour, Sandrine ; Andreadou, Ioanna ; Bøtker, Hans Erik ; Davidson, Sean M. ; Heusch, Gerd ; Ruiz-Meana, Marisol ; Schulz, Rainer ; Zuurbier, Coert J. ; Ferdinandy, Péter ; Hausenloy, Derek J.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2021-12, Vol.116 (1), p.52-52, Article 52
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ArticlesFull Text
Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence
Author / Creator:Pišlar, Anja ; Tratnjek, Larisa ; Glavan, Gordana ; Nace Zidar ; Živin, Marko ; Kos, Janko
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-01
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ArticlesPeer ReviewedFull Text
High-performance liquid chromatography evaluation of lipophilicity and QSRR modeling of a series of dual DNA gyrase and topoisomerase IV inhibitors
Author / Creator:Dobričić, Vladimir ; Savić, Jelena ; Tomašič, Tihomir ; Durcik, Martina ; Zidar, Nace ; Mašič, Lucija Peterlin ; Ilaš, Janez ; Kikelj, Danijel ; Čudina, Olivera
Publisher:Budapest: Akademiai Kiado Zrt
Journal title:Acta chromatographica, 2024-03, Vol.36 (1), p.45-51
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ArticlesPeer ReviewedFull Text
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues
Author / Creator:Zidar, Nace ; Montalvão, Sofia ; Hodnik, Žiga ; Nawrot, Dorota A ; Žula, Aleš ; Ilaš, Janez ; Kikelj, Danijel ; Tammela, Päivi ; Mašič, Lucija Peterlin
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2014-02, Vol.12 (2), p.940-963
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ArticlesPeer ReviewedFull Text
Second-generation 4,5,6,7-tetrahydrobenzo[ d ]thiazoles as novel DNA gyrase inhibitors
Author / Creator:Lamut, Andraž ; Skok, Žiga ; Barančoková, Michaela ; Gutierrez, Lucas J ; Cruz, Cristina D ; Tammela, Päivi ; Draskovits, Gábor ; Szili, Petra Éva ; Nyerges, Ákos ; Pál, Csaba ; Molek, Peter ; Bratkovič, Tomaž ; Ilaš, Janez ; Zidar, Nace ; Zega, Anamarija ; Enriz, Ricardo D ; Kikelj, Danijel ; Tomašič, Tihomir
Publisher:England: Newlands Press
Journal title:Future medicinal chemistry, 2020-02, Vol.12 (4), p.277-297
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ArticlesPeer ReviewedFull Text
Cathepsin H indirectly regulates morphogenetic protein-4 (BMP-4) in various human cell lines
Author / Creator:Rojnik, Matija ; Jevnikar, Zala ; Mirkovic, Bojana ; Janes, Damjan ; Zidar, Nace ; Kikelj, Danijel ; Kos, Janko
Publisher:Poland: De Gruyter Poland
Journal title:Radiology and oncology, 2011-12, Vol.45 (4), p.259-266
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ArticlesPeer ReviewedFull Text
Benzoxazine Series of Histidine Kinase Inhibitors as Potential Antimicrobial Agents with Activity against Enterococci
Author / Creator:Mueller-Premru, Manica ; Zidar, Nace ; Cvitković Špik, Vesna ; Krope, Adrijana ; Kikelj, Danijel
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Chemotherapy (Basel), 2009-01, Vol.55 (6), p.414-417
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Rational design of balanced dual-targeting antibiotics with limited resistance

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Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation

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Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors

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Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

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Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors

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Enhancing Antibacterial Efficacy: Combining Novel Bacterial Topoisomerase Inhibitors with Efflux Pump Inhibitors and Other Agents Against Gram-Negative Bacteria

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Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

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Action of clathrodin and analogues on voltage-gated sodium channels

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IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action

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Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

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High-performance liquid chromatography evaluation of lipophilicity and QSRR modeling of a series of dual DNA gyrase and topoisomerase IV inhibitors

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Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues

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Second-generation 4,5,6,7-tetrahydrobenzo[ d ]thiazoles as novel DNA gyrase inhibitors

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Cathepsin H indirectly regulates morphogenetic protein-4 (BMP-4) in various human cell lines

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Benzoxazine Series of Histidine Kinase Inhibitors as Potential Antimicrobial Agents with Activity against Enterococci

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