Characterizing mutagenic effects of recombination through a sequence-level genetic map
Characterizing mutagenic effects of recombination through a sequence-level genetic map
About this item
Full title
Author / Creator
Halldorsson, Bjarni V. , Palsson, Gunnar , Stefansson, Olafur A. , Jonsson, Hakon , Hardarson, Marteinn T. , Eggertsson, Hannes P. , Gunnarsson, Bjarni , Oddsson, Asmundur , Halldorsson, Gisli H. , Zink, Florian , Gudjonsson, Sigurjon A. , Frigge, Michael L. , Thorleifsson, Gudmar , Sigurdsson, Asgeir , Stacey, Simon N. , Sulem, Patrick , Masson, Gisli , Helgason, Agnar , Gudbjartsson, Daniel F. , Thorsteinsdottir, Unnur and Stefansson, Kari
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Genetic diversity arises from recombination and de novo mutation (DNM). Using a combination of microarray genotype and whole-genome sequence data on parent-child pairs, we identified 4,531,535 crossover recombinations and 200,435 DNMs. The resulting genetic map has a resolution of 682 base pairs. Crossovers exhibit a mutagenic effect, with overrepr...
Alternative Titles
Full title
Characterizing mutagenic effects of recombination through a sequence-level genetic map
Authors, Artists and Contributors
Author / Creator
Palsson, Gunnar
Stefansson, Olafur A.
Jonsson, Hakon
Hardarson, Marteinn T.
Eggertsson, Hannes P.
Gunnarsson, Bjarni
Oddsson, Asmundur
Halldorsson, Gisli H.
Zink, Florian
Gudjonsson, Sigurjon A.
Frigge, Michael L.
Thorleifsson, Gudmar
Sigurdsson, Asgeir
Stacey, Simon N.
Sulem, Patrick
Masson, Gisli
Helgason, Agnar
Gudbjartsson, Daniel F.
Thorsteinsdottir, Unnur
Stefansson, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2170964081
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2170964081
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aau1043
