Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic ph...
Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Existing high-throughput methods to identify RNA-binding proteins (RBPs) are based on capture of polyadenylated RNAs and cannot recover proteins that interact with nonadenylated RNAs, including long noncoding RNA, pre-mRNAs and bacterial RNAs. We present orthogonal organic phase separation (OOPS), which does not require molecular tagging or capture...
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Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)
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TN_cdi_proquest_journals_2175871562
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2175871562
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-018-0001-2
