Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis
Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis
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Author / Creator
Li, Zehua , Wu, Zhiye , Yan, Jianyun , Liu, Hailin , Liu, Qicai , Deng, Yi , Ou, Caiwen and Chen, Minsheng
Publisher
New York: Elsevier Inc
Journal title
Language
English
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Publisher
New York: Elsevier Inc
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Scope and Contents
Contents
Trimethylamine N-oxide (TMAO), a gut microbe-derived metabolite of dietary choline and other trimethylamine-containing nutrients, has been linked to increased cardiovascular disease risk. It is unknown whether TMAO plays a role in the development of cardiac hypertrophy. Transverse aortic constriction (TAC) was performed to induce cardiac hypertroph...
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Full title
Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis
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Record Identifier
TN_cdi_proquest_journals_2186152570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2186152570
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/s41374-018-0091-y