Intracerebroventricular infusion of CHO5, a rat monoclonal antibody directed against mouse low-affin...
Intracerebroventricular infusion of CHO5, a rat monoclonal antibody directed against mouse low-affinity nerve growth factor receptor (p75NTR), specifically labels basal forebrain cholinergic neurons in mouse brain
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Author / Creator
Rossner, S , Schliebs, R and Bigl, V
Publisher
United States: Springer Nature B.V
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Language
English
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Publisher
United States: Springer Nature B.V
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Contents
The finding that basal forebrain cholinergic cells are specifically endowed with the low-affinity nerve growth factor receptor p75NTR has been employed to develop a cholinergic immunotoxin in rats by covalently linking the monoclonal antibody 192IgG against the rat p75NTR with the cytotoxic protein saporin (192IgG-saporin). Following intracebrovent...
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Full title
Intracerebroventricular infusion of CHO5, a rat monoclonal antibody directed against mouse low-affinity nerve growth factor receptor (p75NTR), specifically labels basal forebrain cholinergic neurons in mouse brain
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Record Identifier
TN_cdi_proquest_journals_221119479
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_221119479
Other Identifiers
ISSN
0885-7490
E-ISSN
1573-7365
DOI
10.1007/BF02680011
