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Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regen...

Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2218687391

Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regeneration

About this item

Full title

Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regeneration

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

In addition to changed gene expression, pathological cytoskeletal dynamics in the axon is another key intrinsic barrier for axon regeneration in the central nervous system (CNS). Here we showed that knocking out myosin IIA/B in retinal ganglion cells alone was sufficient to induce marked and sustained optic nerve regeneration. Combined Lin28 overex...

Alternative Titles

Full title

Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2218687391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2218687391

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/625707