A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic...
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The physicochemical properties of nucleic acids are dominated by their highly charged phosphodiester backbone chemistry. This polyelectrolyte structure decouples information content (base sequence) from bulk properties, such as solubility, and has been proposed as a defining trait of all informational polymers. However, this conjecture has not been...
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Full title
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
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TN_cdi_proquest_journals_2229623985
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2229623985
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-019-0255-4
