Approximations of the target-mediated drug disposition model and identifiability of model parameters
Approximations of the target-mediated drug disposition model and identifiability of model parameters
About this item
Full title
Author / Creator
Publisher
Boston: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
Boston: Springer US
Subjects
More information
Scope and Contents
Contents
Models for drugs exhibiting target-mediated drug disposition (TMDD) play an important role in the investigation of biological products (Mager and Jusko 2001). These models are often overparameterized and difficult to converge. A simpler quasi-equilibrium (QE) approximation of the general model has been suggested (Mager and Krzyzanski 2005), but eve...
Alternative Titles
Full title
Approximations of the target-mediated drug disposition model and identifiability of model parameters
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_224115481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_224115481
Other Identifiers
ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1007/s10928-008-9102-8
