Passenger Hotspot Mutations in Cancer
Passenger Hotspot Mutations in Cancer
About this item
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Hotspots, or mutations that recur at the same genomic site across multiple tumors, have been conventionally interpreted as strong universal evidence of somatic positive selection, unequivocally pinpointing genes driving tumorigenesis. Here, we demonstrate that this convention is falsely premised on an inaccurate statistical model of background muta...
Alternative Titles
Full title
Passenger Hotspot Mutations in Cancer
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Record Identifier
TN_cdi_proquest_journals_2243171503
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2243171503
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/675801
How to access this item
https://www.proquest.com/docview/2243171503?pq-origsite=primo&accountid=13902
