Early Sedation with Dexmedetomidine in Critically Ill Patients
Early Sedation with Dexmedetomidine in Critically Ill Patients
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Author / Creator
Shehabi, Yahya , Howe, Belinda D , Bellomo, Rinaldo , Arabi, Yaseen M , Bailey, Michael , Bass, Frances E , Bin Kadiman, Suhaini , McArthur, Colin J , Murray, Lynnette , Reade, Michael C , Seppelt, Ian M , Takala, Jukka , Wise, Matt P , Webb, Steven A and ANZICS Clinical Trials Group and the SPICE III Investigators
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
In a randomized trial involving 4000 patients in the ICU who required sedation for mechanical ventilation, dexmedetomidine had no benefit on 90-day mortality as compared with usual care and was associated with more adverse events. Additional drugs were required for prescribed sedation levels in the two groups.
Alternative Titles
Full title
Early Sedation with Dexmedetomidine in Critically Ill Patients
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Record Identifier
TN_cdi_proquest_journals_2247764422
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2247764422
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1904710