Log in to save to my catalogue

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human...

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2263277472

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma

About this item

Full title

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2019-08, Vol.99 (8), p.1117-1129

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

B7H3 (CD276), a co-stimulator molecule of the cell surface B7 protein superfamily, is expressed on glioblastomas (GBM). Recently, B7H3 functions beyond immune costimulation have been demonstrated. However, the mechanisms underlying B7H3 function are diverse and not well understood. GBM tumors contain undifferentiated self-renewing cells, which conf...

Alternative Titles

Full title

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2263277472

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2263277472

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/s41374-019-0238-5

How to access this item