Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma
Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma
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Author / Creator
Jerby, Livnat , Neftel, Cyril , Shore, Marni E , Mcbride, Matthew J , Haas, Brian , Izar, Benjamin , Weissman, Hannah R , Volorio, Angela , Boulay, Gaylor , Cironi, Luisa , Richman, Alyssa R , Broye, Liliane C , Gurski, Joseph M , Luo, Christina C , Mylvaganam, Ravindra , Nguyen, Lan , Mei, Shaolin , Melms, Johannes C , Georgescu, Christophe , Cohen, Ofir , Buendia-Buendia, Jorge E , Cuoco, Michael S , Labes, Danny , Zollinger, Daniel R , Beechem, Joseph M , Nielsen, Petur , Chebib, Ivan , Cote, Gregory , Choy, Edwin , Letovanec, Igor , Cherix, Stephane , Wagle, Nikhil , Sorger, Peter K , Haynes, Alex B , Mullen, John T , Stamenkovic, Ivan , Rivera, Miguel N , Kadoch, Cigall , Rozenblatt-Rosen, Orit , Suva, Mario L , Riggi, Nicolo and Regev, Aviv
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Synovial sarcoma is an aggressive mesenchymal neoplasm, driven by the SS18-SSX fusion, and characterized by immunogenic antigens expression and exceptionally low T cell infiltration levels. To study the cancer-immune interplay in this disease, we profiled 16,872 cells from 12 human synovial sarcoma tumors using single-cell RNA-sequencing (scRNA-Seq...
Alternative Titles
Full title
Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma
Authors, Artists and Contributors
Author / Creator
Neftel, Cyril
Shore, Marni E
Mcbride, Matthew J
Haas, Brian
Izar, Benjamin
Weissman, Hannah R
Volorio, Angela
Boulay, Gaylor
Cironi, Luisa
Richman, Alyssa R
Broye, Liliane C
Gurski, Joseph M
Luo, Christina C
Mylvaganam, Ravindra
Nguyen, Lan
Mei, Shaolin
Melms, Johannes C
Georgescu, Christophe
Cohen, Ofir
Buendia-Buendia, Jorge E
Cuoco, Michael S
Labes, Danny
Zollinger, Daniel R
Beechem, Joseph M
Nielsen, Petur
Chebib, Ivan
Cote, Gregory
Choy, Edwin
Letovanec, Igor
Cherix, Stephane
Wagle, Nikhil
Sorger, Peter K
Haynes, Alex B
Mullen, John T
Stamenkovic, Ivan
Rivera, Miguel N
Kadoch, Cigall
Rozenblatt-Rosen, Orit
Suva, Mario L
Riggi, Nicolo
Regev, Aviv
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TN_cdi_proquest_journals_2268233113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2268233113
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E-ISSN
2692-8205
DOI
10.1101/724302
How to access this item
https://www.proquest.com/docview/2268233113?pq-origsite=primo&accountid=13902