Long-term high-dose interferon-[alpha] therapy delays Hepadnavirus-related hepatocarcinogenesis in X...
Long-term high-dose interferon-[alpha] therapy delays Hepadnavirus-related hepatocarcinogenesis in X/myc transgenic mice
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New York: Nature Publishing Group
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English
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New York: Nature Publishing Group
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The role of interferon-alpha (IFN-alpha) remains unclear in prevention of virus-induced hepatocellular carcinoma in humans. We have investigated it herewith in the X/myc transgenic mouse model of Hepadnavirus-related hepatocarcinogenesis because of upregulation of c-myc oncogene in the liver. We have demonstrated that IFN-alpha can downregulate dos...
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Long-term high-dose interferon-[alpha] therapy delays Hepadnavirus-related hepatocarcinogenesis in X/myc transgenic mice
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TN_cdi_proquest_journals_227343991
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_227343991
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0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206375
