Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma
Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma
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Full title
Author / Creator
Chari, Ajai , Vogl, Dan T , Gavriatopoulou, Maria , Nooka, Ajay K , Yee, Andrew J , Huff, Carol A , Moreau, Philippe , Dingli, David , Cole, Craig , Lonial, Sagar , Dimopoulos, Meletios , Stewart, A. Keith , Richter, Joshua , Vij, Ravi , Tuchman, Sascha , Raab, Marc S , Weisel, Katja C , Delforge, Michel , Cornell, Robert F , Kaminetzky, David , Hoffman, James E , Costa, Luciano J , Parker, Terri L , Levy, Moshe , Schreder, Martin , Meuleman, Nathalie , Frenzel, Laurent , Mohty, Mohamad , Choquet, Sylvain , Schiller, Gary , Comenzo, Raymond L , Engelhardt, Monika , Illmer, Thomas , Vlummens, Philip , Doyen, Chantal , Facon, Thierry , Karlin, Lionel , Perrot, Aurore , Podar, Klaus , Kauffman, Michael G , Shacham, Sharon , Li, Lingling , Tang, Shijie , Picklesimer, Carla , Saint-Martin, Jean-Richard , Crochiere, Marsha , Chang, Hua , Parekh, Samir , Landesman, Yosef , Shah, Jatin , Richardson, Paul G and Jagannath, Sundar
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Selinexor, a drug that inhibits nuclear export of tumor suppressor proteins, was tested in a phase 2 trial involving patients with myeloma whose disease had progressed despite treatment with proteasome inhibitors, immunomodulatory agents, alkylating agents, and monoclonal antibodies. A partial response or better was observed in 26% of patients, and...
Alternative Titles
Full title
Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma
Authors, Artists and Contributors
Author / Creator
Vogl, Dan T
Gavriatopoulou, Maria
Nooka, Ajay K
Yee, Andrew J
Huff, Carol A
Moreau, Philippe
Dingli, David
Cole, Craig
Lonial, Sagar
Dimopoulos, Meletios
Stewart, A. Keith
Richter, Joshua
Vij, Ravi
Tuchman, Sascha
Raab, Marc S
Weisel, Katja C
Delforge, Michel
Cornell, Robert F
Kaminetzky, David
Hoffman, James E
Costa, Luciano J
Parker, Terri L
Levy, Moshe
Schreder, Martin
Meuleman, Nathalie
Frenzel, Laurent
Mohty, Mohamad
Choquet, Sylvain
Schiller, Gary
Comenzo, Raymond L
Engelhardt, Monika
Illmer, Thomas
Vlummens, Philip
Doyen, Chantal
Facon, Thierry
Karlin, Lionel
Perrot, Aurore
Podar, Klaus
Kauffman, Michael G
Shacham, Sharon
Li, Lingling
Tang, Shijie
Picklesimer, Carla
Saint-Martin, Jean-Richard
Crochiere, Marsha
Chang, Hua
Parekh, Samir
Landesman, Yosef
Shah, Jatin
Richardson, Paul G
Jagannath, Sundar
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2277529203
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2277529203
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1903455
