DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosom...
DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosome Scale Losses
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Background We previously showed that a major driver of cancer chromosomal instability (CIN) is replication stress, the slowing or stalling of DNA replication. However, the precise drivers of replication stress in cancer and the mechanisms by which these cause CIN and influence tumour evolution remain unclear. Common fragile sites are well-...
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DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosome Scale Losses
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TN_cdi_proquest_journals_2277750464
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2277750464
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E-ISSN
2692-8205
DOI
10.1101/743658
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https://www.proquest.com/docview/2277750464?pq-origsite=primo&accountid=13902
