The role of telomeres and telomerase in cirrhosis and liver cancer
The role of telomeres and telomerase in cirrhosis and liver cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Telomerase is a key enzyme for cell survival that prevents telomere shortening and the subsequent cellular senescence that is observed after many rounds of cell division. In contrast, inactivation of telomerase is observed in most cells of the adult liver. Absence of telomerase activity and shortening of telomeres has been implicated in hepatocyte...
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Full title
The role of telomeres and telomerase in cirrhosis and liver cancer
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TN_cdi_proquest_journals_2281950433
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2281950433
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ISSN
1759-5045
E-ISSN
1759-5053
DOI
10.1038/s41575-019-0165-3
