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Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin

Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_228305101

Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin

About this item

Full title

Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2008-10, Vol.15 (10), p.1067-1075

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The binding of kinesin to microtubules promotes nucleotide exchange by the kinesin. Structural studies of the intermediate states of nucleotide exchange reveal the sequence of interactions and conformational changes that occur and the role of Mg
2+
in the process, providing a testable model for microtubule-activated ADP release.
Mg-ADP rel...

Alternative Titles

Full title

Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_228305101

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_228305101

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.1487

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