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Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2287464847

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

About this item

Full title

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2019-09, Vol.25 (9), p.1428-1441

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Psychological distress has long been suspected to influence cancer incidence and mortality. It remains largely unknown whether and how stress affects the efficacy of anticancer therapies. We observed that social defeat caused anxiety-like behaviors in mice and dampened therapeutic responses against carcinogen-induced neoplasias and transplantable t...

Alternative Titles

Full title

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2287464847

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2287464847

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-019-0566-4

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