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The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature aud...

The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature aud...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2289722777

The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

About this item

Full title

The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

Publisher

Frankfurt: EMBO Press

Journal title

EMBO molecular medicine, 2014-07, Vol.6 (7), p.984-992

Language

English

Formats

Publication information

Publisher

Frankfurt: EMBO Press

More information

Scope and Contents

Contents

Protocadherin‐15 (Pcdh15) is a component of the tip‐links, the extracellular filaments that gate hair cell mechano‐electrical transduction channels in the inner ear. There are three Pcdh15 splice isoforms (CD1, CD2 and CD3), which only differ by their cytoplasmic domains; they are thought to function redundantly in mechano‐electrical transduction d...

Alternative Titles

Full title

The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2289722777

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2289722777

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201403976

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