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Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2293374419

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

About this item

Full title

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Objective: Diabetes is characterized by pancreatic β-cell dedifferentiation. Dedifferentiating β-cells inappropriately metabolize lipids over carbohydrates and exhibit impaired mitochondrial oxidative phosphorylation. However, the mechanism linking the β-cell's response to an adverse metabolic environment with impaired mitochondrial function remain...

Alternative Titles

Full title

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2293374419

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2293374419

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/774364