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Progranulin sustains STAT 3 hyper‐activation and oncogenic function in colorectal cancer cells

Progranulin sustains STAT 3 hyper‐activation and oncogenic function in colorectal cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2297847940

Progranulin sustains STAT 3 hyper‐activation and oncogenic function in colorectal cancer cells

About this item

Full title

Progranulin sustains STAT 3 hyper‐activation and oncogenic function in colorectal cancer cells

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2019-10, Vol.13 (10), p.2142-2159

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Persistent activation of Signal Transducer and Activator of Transcription (
STAT
)3 occurs in a high percentage of tumors, including colorectal cancer (
CRC
), thereby contributing to malignant cell proliferation and survival. Although
STAT
3 is recognized as an attractive therapeutic target in
CRC
, conventional approaches...

Alternative Titles

Full title

Progranulin sustains STAT 3 hyper‐activation and oncogenic function in colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2297847940

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2297847940

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1002/1878-0261.12552

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