Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat...
Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Background: The transcription factor Nurr1 has been identified to be ectopically induced in the striatum of dyskinetic rodents expressing L-DOPA-induced dyskinesia (LID). In the present study, we sought to characterize Nurr1 as a causative factor in LID expression. Methods: We used rAAV2/5 to overexpress Nurr1 or GFP in the parkinsonian striatum of...
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Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease
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TN_cdi_proquest_journals_2298928426
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2298928426
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2692-8205
DOI
10.1101/768374
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https://www.proquest.com/docview/2298928426?pq-origsite=primo&accountid=13902
