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Manfredsson, Fredric P
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: LIT-MEK, 2022, p.7246-7246
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Manfredsson, Fredric P
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: LIU-MEM, 2021, p.7219-7219
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ArticlesPeer ReviewedFull Text
A Method for Combining RNAscope In Situ Hybridization with Immunohistochemistry in Thick Free-Floating Brain Sections and Primary Neuronal Cultures
Author / Creator:Grabinski, Tessa M. ; Kneynsberg, Andrew ; Manfredsson, Fredric P. ; Kanaan, Nicholas M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0120120-e0120120
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Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus
Author / Creator:Kang, Seong Su ; Liu, Xia ; Ahn, Eun Hee ; Xiang, Jie ; Manfredsson, Fredric P. ; Yang, Xifei ; Luo, Hongbo R. ; Liles, L. Cameron ; Weinshenker, David ; Ye, Keqiang
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-01, Vol.130 (1), p.422-437
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C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease
Author / Creator:Wang, Zhi-Hao ; Gong, Ke ; Liu, Xia ; Zhang, Zhentao ; Sun, Xiaoou ; Wei, Zheng Zachory ; Yu, Shan Ping ; Manfredsson, Fredric P. ; Sandoval, Ivette M. ; Johnson, Peter F. ; Jia, Jianping ; Wang, Jian-Zhi ; Ye, Keqiang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.1784-16, Article 1784
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Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinson’s Model
Author / Creator:Lai, Jessica IChi ; Porcu, Alessandra ; Romoli, Benedetto ; Keisler, Maria ; Manfredsson, Fredric P. ; Powell, Susan B. ; Dulcis, Davide
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-02, Vol.24 (4), p.4204
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ArticlesPeer ReviewedFull Text
TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease
Author / Creator:Kang, Seong Su ; Zhang, Zhentao ; Liu, Xia ; Manfredsson, Fredric P. ; Benskey, Matthew J. ; Cao, Xuebing ; Xu, Jun ; Sun, Yi E. ; Ye, Keqiang
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (40), p.10773-10778
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Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease
Author / Creator:Zhang, Zhentao ; Kang, Seong Su ; Liu, Xia ; Ahn, Eun Hee ; Zhang, Zhaohui ; He, Li ; Iuvone, P Michael ; Duong, Duc M ; Seyfried, Nicholas T ; Benskey, Matthew J ; Manfredsson, Fredric P ; Jin, Lingjing ; Sun, Yi E ; Wang, Jian-Zhi ; Ye, Keqiang
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2017-08, Vol.24 (8), p.632-642
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A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates
Author / Creator:Anwer, Danish M. ; Gubinelli, Francesco ; Kurt, Yunus A. ; Sarauskyte, Livija ; Jacobs, Febe ; Venuti, Chiara ; Sandoval, Ivette M. ; Yang, Yiyi ; Stancati, Jennifer ; Mazzocchi, Martina ; Brandi, Edoardo ; O’Keeffe, Gerard ; Steece-Collier, Kathy ; Li, Jia-Yi ; Deierborg, Tomas ; Manfredsson, Fredric P. ; Davidsson, Marcus ; Heuer, Andreas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2023-05, Vol.18 (5), p.e0284480-e0284480
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ArticlesPeer ReviewedFull Text
Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologies
Author / Creator:Xiang, Jie ; Wang, Zhi-Hao ; Ahn, Eun Hee ; Liu, Xia ; Yu, Shan-Ping ; Manfredsson, Fredric P. ; Sandoval, Ivette M. ; Ju, Gong ; Wu, Shengxi ; Ye, Keqiang
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (18), p.9094-9102
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ArticlesPeer ReviewedFull Text
Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System
Author / Creator:Gombash, Sara E. ; Manfredsson, Fredric P. ; Kemp, Christopher J. ; Kuhn, Nathan C. ; Fleming, Sheila M. ; Egan, Ann E. ; Grant, Laura M. ; Ciucci, Michelle R. ; MacKeigan, Jeffrey P. ; Sortwell, Caryl E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-11, Vol.8 (11), p.e81426-e81426
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ArticlesPeer ReviewedFull Text
Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9
Author / Creator:Chatterjee, Diptaman ; Marmion, David J. ; McBride, Jodi L. ; Manfredsson, Fredric P. ; Butler, David ; Messer, Anne ; Kordower, Jeffrey H.
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2022-06, Vol.29 (6), p.390-397
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Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease
Author / Creator:Gordevicius, Juozas ; Li, Peipei ; Marshall, Lee L. ; Killinger, Bryan A. ; Lang, Sean ; Ensink, Elizabeth ; Kuhn, Nathan C. ; Cui, Wei ; Maroof, Nazia ; Lauria, Roberta ; Rueb, Christina ; Siebourg-Polster, Juliane ; Maliver, Pierre ; Lamp, Jared ; Vega, Irving ; Manfredsson, Fredric P. ; Britschgi, Markus ; Labrie, Viviane
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.5134-5134, Article 5134
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A comparison of AAV-vector production methods for gene therapy and preclinical assessment
Author / Creator:Davidsson, Marcus ; Negrini, Matilde ; Hauser, Swantje ; Svanbergsson, Alexander ; Lockowandt, Marcus ; Tomasello, Giuseppe ; Manfredsson, Fredric P. ; Heuer, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.21532-21532, Article 21532
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Corrigendum: The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson's disease
Author / Creator:Lipari, Natalie ; Galfano, Ashley ; Venkatesh, Shruti ; Grezenko, Han ; Sandoval, Ivette M. ; Manfredsson, Fredric P. ; Bishop, Christopher
Publisher:Switzerland: Frontiers Media S.A
Journal title:Frontiers in neural circuits, 2025-04, Vol.19, p.1593235
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Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity
Author / Creator:Benskey, Matthew J. ; Sellnow, Rhyomi C. ; Sandoval, Ivette M. ; Sortwell, Caryl E. ; Lipton, Jack W. ; Manfredsson, Fredric P.
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in molecular neuroscience, 2018-02, Vol.11, p.36-36
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ArticlesPeer ReviewedFull Text
The Future of GDNF in Parkinson's Disease
Author / Creator:Manfredsson, Fredric P. ; Polinski, Nicole K. ; Subramanian, Thyagarajan ; Boulis, Nicholas ; Wakeman, Dustin R. ; Mandel, Ronald J.
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2020-12, Vol.12, p.593572-593572
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Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates
Author / Creator:Collier, Timothy J. ; Redmond, D. Eugene ; Steece-Collier, Kathy ; Lipton, Jack W. ; Manfredsson, Fredric P.
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2016-01, Vol.10, p.12-12
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The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson’s disease
Author / Creator:Lipari, Natalie ; Galfano, Ashley ; Venkatesh, Shruti ; Grezenko, Han ; Sandoval, Ivette M. ; Manfredsson, Fredric P. ; Bishop, Christopher
Publisher:Switzerland: Frontiers Media S.A
Journal title:Frontiers in neural circuits, 2024-11, Vol.18, p.1463941
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phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease
Author / Creator:Gorbatyuk, Oleg S ; Li, Shoudong ; Sullivan, Layla F ; Chen, Weijun ; Kondrikova, Galina ; Manfredsson, Fredric P ; Mandel, Ronald J ; Muzyczka, Nicholas
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (2), p.763-768
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Showing 1 to 20 of 68 results

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Manfredsson, Fredric P

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Manfredsson, Fredric P

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A Method for Combining RNAscope In Situ Hybridization with Immunohistochemistry in Thick Free-Floating Brain Sections and Primary Neuronal Cultures

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Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus

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C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease

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Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinson’s Model

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TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease

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Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease

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A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates

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Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologies

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Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System

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Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9

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Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease

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A comparison of AAV-vector production methods for gene therapy and preclinical assessment

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Corrigendum: The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson's disease

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Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity

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The Future of GDNF in Parkinson's Disease

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Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates

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The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson’s disease

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phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease

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