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The DNA damage response regulates the oocyte pool in mammals

The DNA damage response regulates the oocyte pool in mammals

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2308330701

The DNA damage response regulates the oocyte pool in mammals

About this item

Full title

The DNA damage response regulates the oocyte pool in mammals

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Mammalian oogonia proliferate without completing cytokinesis producing germ cell cysts. Within these cysts, oocytes differentiate and enter meiosis, promote genome-wide double-strand break (DSBs) formation which repair by homologous recombination leads to synapsis of the homologous chromosomes. Errors in homologous recombination or synapsis trigger...

Alternative Titles

Full title

The DNA damage response regulates the oocyte pool in mammals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2308330701

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2308330701

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/816488