The DNA damage response regulates the oocyte pool in mammals
The DNA damage response regulates the oocyte pool in mammals
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Mammalian oogonia proliferate without completing cytokinesis producing germ cell cysts. Within these cysts, oocytes differentiate and enter meiosis, promote genome-wide double-strand break (DSBs) formation which repair by homologous recombination leads to synapsis of the homologous chromosomes. Errors in homologous recombination or synapsis trigger...
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Full title
The DNA damage response regulates the oocyte pool in mammals
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TN_cdi_proquest_journals_2308330701
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2308330701
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E-ISSN
2692-8205
DOI
10.1101/816488
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https://www.proquest.com/docview/2308330701?pq-origsite=primo&accountid=13902